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Fucoidan, derived from brown seaweed, is rapidly growing in popularity among consumers to support a number of important bodily functions.  Animal and cell culture studies have shown fucoidan can enhance the immune system, improve cellular communication, exhibit strong anticoagulant and antithrombotic activity, and inhibit certain cancers and viruses.

The primary active ingredient of Fucoidan is fucose, a sulfated polysaccharide, and one of the eight essential biological sugars that have recently been identified as being absolutely essential for cell-to-cell communication through glycoproteins and glycolipids. Typically only glucose and galactose are contained in the foods we eat. We typically don't consume fucose and so we must produce over thirty-four different enzymatic reactions to generate intermediate molecules to make fucose. During the conversion process if there is a problem in any step (due to toxins, stress etc) our bodies may be robbed of this valuable compound.

Over the past several years, Beijing Gingko Group has realized the potential for this important compound and secured relationships with several leading harvesters of brown seaweed to take advantage of the different species found throughout the oceans of the world.  Each species has its own history of traditional use and it appears that varying chemical compositions lend themselves to certain areas of research.

Beijing Gingko Group currently produces four different species of fucoidan from the following brown seaweeds: Cladosiphon okamuranus (Mozuku), Ascophyllum nodosum (Knotted Wrack), Laminaria japonica (Kombu) and Undaria pinnatifida (Wakame). All fucoidan species are sourced exclusively from pre-screened cultivators and harvesters to ensure consistent species selection and protection of the local environment through the appropriate safeguards.

  Species offering:
 
  Dosage

  FucoMax Fucoidan daily dose     recommendation is 300-900 mg/day     depending on species and application, but   can be increased to 1-5g/day when   necessary.

  Stability
  FucoMaxFucoidan stability under   normal storage conditions is at least 36   months after the date of manufacture.
Introduction to Fucoidan
About Beijing Gingko Group

Beijing Gingko Group
is a leading Chinese company specializing in the manufacturing of botanical derivatives for the pharmaceutical, cosmetics, food and food supplement, beverage, and nutrition industries worldwide.  It is also the first Chinese company to be certified by GeneScan for its IP Non-GMO products. The FucoMax™ Fucoidan product line, produced by Beijing Gingko Group (BGG), is extracted from Cladosiphon okamuranus, Ascophyllum nodosum,  Laminaria japonica and Undaria pinnatifida. BGG has extracted and perfected these delicate compounds using highly selected brown seaweeds which are collected in natural, deep and cold oceanic waters under excellent growth conditions, such as Norway (Ascophyllum nodosum), Japan (Cladosiphon okamuranus) and the East Sea of China (Laminaria japonica and Undaria pinnatifida). There is no contamination around these bodies of water. The seaweeds are harvested by cutting fresh seaweeds that float to the surface, rather than by dredging, to reduce contamination and minimize any potential environmental impacts. With the company's proprietary extraction method, utilizing a low temperature water extraction process, BGG makes highly purified fucoidan with potencies reaching 90%. 

In addition to manufacturing FucoMax™ Fucoidan, BGG manufactures
over 100 specialty plant extracts that sell throughout the world under the Ginnovay TM brand name. BGG is also the dominant global supplier of European Bilberry Extract (Vaccinium myrtillus) and produces other products such as black soybean extract, policosanol-octacosanol, natural vitamin E (Tocotrienols & Tocopherols), black currant extract, natural vitamin C, juice concentrates and more.
Cladosiphon okamuranus
Fucoidan from Cladosiphon okamuranus has
been shown in animal and cell culture studies to inhibit irritable bowel disease1, gastric ulcers2,3, gastric cancer4,5 and induce cancer cell apoptosis6.
Ascophyllum nodosum
Fucoidan from Ascophyllum nodosum has been shown to inhibit tumor growth7 and act as an anticoagulant8.
Laminaria japonica
Fucoidan from Laminaria japonica has been shown to inhibit tumor growth9, 10 , act as an anticoagulant11 and shown antiviral activity12.
Undaria pinnatifida
Fucoidan from Undaria pinnatifida has been shown to inhibit tumor growth13, act as an antiviral14 and reduce allergic inflammation15.
References
1.Matsumoto S., et al. Fucoidan derived from Cladosiphon okamuranus Tokida ameliorates murine chronic colitis through the down-regulation of interleukin-6 production on colonic epithelial cells. Clin Exp Immunol. 2004 Jun;136(3):432-9.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15147344&query_hl=2&itool=pubmed_docsum
2. Shibata H, et al. Effect of oligofucose derivatives on acetic acid-induced gastric ulcer in rats. Biomed Mater Eng. 2001;11(1):55-61.
http://iospress.metapress.com/(gnrjqy2nsyb0eq55fvktjl45)/app/home/contribution.asp?referrer=parent&backto=issue,6,7;journal,29,42;linkingpublicationresults,1:103145,1
3. Shibata H, et al. Properties of fucoidan from Cladosiphon okamuranus tokida in gastric mucosal protection. Biofactors. 2000;11(4):235-45.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11270504&query_hl=8&itool=pubmed_DocSum
4. Sakai T, et al. Structures of oligosaccharides derived from Cladosiphon okamuranus fucoidan by digestion with marine bacterial enzymes. Mar Biotechnol (NY). 2003 Nov-Dec;5(6):536-44. Epub 2003 Jul 17.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=14730423&query_hl=9&itool=pubmed_docsum
5. Shibata H, et al. Inhibitory effect of Cladosiphon fucoidan on the adhesion of Helicobacter pylori to human gastric cells. J Nutr Sci Vitaminol (Tokyo). 1999 Jun;45(3):325-36.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=10524351&query_hl=7&itool=pubmed_docsum
6. Haneji K, et al. Fucoidan extracted from Cladosiphon okamuranus Tokida induces apoptosis of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells. Nutr Cancer. 2005;52(2):189-201.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16201850&query_hl=12&itool=pubmed_DocSum
7. Riou D, et al. Antitumor and antiproliferative effects of a fucan extracted from ascophyllum nodosum against a non-small-cell bronchopulmonary carcinoma line. Anticancer Res. 1996 May-Jun;16(3A):1213-8.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8702239&query_hl=14&itool=pubmed_DocSum
8. Chevolot L, et al. Further data on the structure of brown seaweed fucans: relationships with anticoagulant activity. Carbohydr Res. 1999 Jun 30;319(1-4):154-65.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11269406&query_hl=16&itool=pubmed_DocSum
9. Chida K, et al. Antitumor activity of a crude fucoidan fraction prepared from the roots of kelp (Laminaria species). Kitasato Arch Exp Med. 1987 Jun;60(1-2):33-9.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=3669501&query_hl=20&itool=pubmed_DocSum
10. Teas J, et al. Dietary seaweed (Laminaria) and mammary carcinogenesis in rats. Cancer Res. 1984 Jul;44(7):2758-61.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=6426785&query_hl=22&itool=pubmed_docsum
11. Pomin VH, et al. Selective cleavage and anticoagulant activity of a sulfated fucan: stereospecific removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity. Glycobiology. 2005 Apr;15(4):369-81. Epub 2004 Dec 8.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15590773&query_hl=24&itool=pubmed_DocSum
12. Romanos MT, et al. A sulphated fucan from the Laminaria abyssalis inhibits the human T cell lymphotropic virus type 1-induced syncytium formation in HeLa cells. Antivir Chem Chemother. 2002 Jul;13(4):219-21.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12495209&query_hl=26&itool=pubmed_DocSum
13. Maruyama H, et al. Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida. In Vivo. 2003 May-Jun;17(3):245-9.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12929574&query_hl=28&itool=pubmed_docsum
14. Lee JB, et al. Novel antiviral fucoidan from sporophyll of Undaria pinnatifida (Mekabu). Chem Pharm Bull (Tokyo). 2004 Sep;52(9):1091-4.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15340195&query_hl=30&itool=pubmed_docsum
15. Maruyama H, et al. Suppression of Th2 immune responses by mekabu fucoidan from Undaria pinnatifida sporophylls. Int Arch Allergy Immunol. 2005 Aug;137(4):289-94. Epub 2005 Jun 17.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15970637&query_hl=28&itool=pubmed_docsum